Tuberculous Meningitis: Diagnostic and Radiological Features, Pathogenesis and Biomarkers
نویسندگان
چکیده
منابع مشابه
Tuberculous Meningitis: Diagnostic and Radiological Features, Pathogenesis and Biomarkers
Central nervous system tuberculosis is the most severe form of extrapulmonary tuberculosis disease. We aim to review the diagnostic and radiological features, pathogenesis, and biomarkers of tuberculous meningitis. We also aim to look at the latest development of research of the disease. The diagnosis of tuberculous (TB) meningitis is difficult because the disease presents with unspecific clini...
متن کاملPathogenesis and immune response in tuberculous meningitis.
Cerebral tuberculosis is the most severe type of extrapulmonary disease that is in developing countries highly predominant in children. Meningeal tuberculosis is the most common form and usually begins with respiratory infection followed by early haematogenous dissemination to extrapulmonary sites involving the brain. In comparison with the lung, Mycobacterium tuberculosis induces a very differ...
متن کاملNeuroimaging features of tuberculous meningitis.
Tuberculous meningitis leads to a high mortality rate. However, it responds well to chemotherapy if the treatment is started early. Neuroimaging is one of the most important initial investigations. There were 42 patients diagnosed with tuberculous meningitis in Kuala Lumpur Hospital based on clinical criteria, cerebrospinal fluid analysis and response to anti-tuberculous treatment over a 7 year...
متن کاملBiomarkers of Cerebral Injury and Inflammation in Pediatric Tuberculous Meningitis
Background Tuberculous meningitis (TBM) leads to death or disability in half the affected individuals. Tools to assess severity and predict outcome are lacking. Neurospecific biomarkers could serve as markers of the severity and evolution of brain injury, but have not been widely explored in TBM. We examined biomarkers of neurological injury (neuromarkers) and inflammation in pediatric TBM and ...
متن کاملA diagnostic rule for tuberculous meningitis.
Diagnostic confusion often exists between tuberculous meningitis and other meningoencephalitides. Newer diagnostic tests are unlikely to be available in many countries for some time. This study examines which clinical features and simple laboratory tests can differentiate tuberculous meningitis from other infections. Two hundred and thirty two children (110 tuberculous meningitis, 94 non-tuberc...
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ژورنال
عنوان ژورنال: Neuroscience and Medicine
سال: 2013
ISSN: 2158-2912,2158-2947
DOI: 10.4236/nm.2013.42016